What are the different types of poikilocytosis? Be sure to tell them about your symptoms or if you’re taking any medications.Įxamples of other diagnostic tests include: Your doctor may ask you questions about your medical history. In addition, your doctor will likely run more tests to find out what’s causing your abnormally shaped RBCs. Your doctor will try to figure out which shape is most prevalent. Sometimes, there are several different types of poikilocytes present in the blood. People with poikilocytosis have normally shaped cells mixed in with abnormally shaped cells. Not every single RBC will take on an abnormal shape. The doctor then views the blood under a microscope, where the sizes and shapes of the RBCs can be seen. This test may be done during a routine physical exam, or if you’re experiencing unexplained symptoms.ĭuring a blood smear, a doctor spreads a thin layer of blood on a microscope slide and stains the blood to help differentiate the cells. Poikilocytosis may be diagnosed during a test called a blood smear. alcoholism or alcohol-related liver diseaseĪll newborn babies in the United States are screened for certain genetic blood disorders, like sickle cell anemia.autoimmune hemolytic anemias, a group of disorders that occur when the immune system mistakenly destroys RBCs.megaloblastic anemia, an anemia typically caused by a deficiency in folate or vitamin B-12.iron-deficiency anemia, the most common form of anemia that occurs when the body doesn’t have enough iron.Symptoms usually come on slowly and begin in mid-adulthoodĪcquired causes of poikilocytosis include: McLeod syndrome, a rare genetic disorder that affects the nerves, heart, blood, and brain.thalassemia, a genetic blood disorder in which the body makes abnormal hemoglobin.sickle cell anemia, a genetic disease characterized by RBCs with an abnormal crescent shape. Inherited causes of poikilocytosis include: Acquired conditions develop later in life. Inherited conditions are caused by a genetic mutation. Poikilocytosis conditions can be inherited or acquired. Poikilocytosis is typically the result of another condition.
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